L. Schillebeeckx MD, L. Marcelis MD, PhD, M. Baldewijns MD, PhD, K. Dewulf MD, C. Mai MD, P. Willemen MD, I. Vanden Bempt MD, PhD, S. Joniau MD, PhD, M. Albersen MD, PhD, W. Everaerts MD, PhD
Stromal tumour of unknown malignant potential (STUMP) is a rare type of mesenchymal tumour of the prostate. These tumours often cause obstructive urinary symptoms, haematuria or haematospermia and can be misdiagnosed as benign prostatic hyperplasia (BPH). STUMP has a variable and unpredictable clinical course. Generally, these tumours have a good prognosis since they are mostly confined to the prostate. However, a minority recurs after surgery and uncommonly can adhere to adjacent organs or (even more rarely) metastasizes. Progression to prostatic stromal sarcoma has rarely been reported. The diagnosis is made on histological examination of prostate tissue (from biopsy or transurethral resection of the prostate (TURP)). The appropriate treatment approach is currently unknown. Treatment recommendations should be based on patient age, treatment preference, size or extent of the lesion. This case report describes a case of a 68-years old man who presented with a STUMP and provides an overview of the literature on this topic.
K. Dewulf MD, A-S. Van Rompuy MD, PhD, G. De Meerleer MD, PhD, K. Goffin MD, PhD, C. Mai MD, H. erlinde Dumez MD, PhD, M. Albersen MD, PhD
Metastatic penile cancer patients have a poor prognosis of six to twelve months with conventional therapies including surgery, cytotoxic chemotherapy and radiotherapy. We present the promising result of the use of an immune checkpoint inhibitor in a metastatic penile cancer patient. A review of the potential for immuno-therapy in penile cancer is presented.