From May 29th till June 2nd, Chicago was host for the 2015 ASCO annual meeting. The theme for this year’s congress was ‘Illumination and Innovation: Transforming Data into Learning’. With over 30,000 registered attendees from over 120 countries worldwide and more than 6,000 submitted abstracts, this year’s meeting was a great success. This report will highlight 12 key studies concerning genitourinary cancers presented during the meeting.

(BELG J MED ONCOL 2015;9:158–63)