Over the past several years, AstraZeneca has received multiple regulatory approvals from the European Medicines Agency (EMA) for the use of osimertinib, durvalumab, and tremelimumab in the treatment of lung cancer. These approvals span various disease stages and histological subtypes and have contributed to significant changes in treatment algorithms for non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC).