Update to the Belgian follow-up guidelines for abnormal cervical screening results

BJMO - volume 16, issue 2, march 2022

C. Bourgain MD, PhD, B. Weynand MD, PhD, K. Van de Vijver MD, PhD, S. Shahebali MD, PhD


The Belgian Society for Clinical Cytology elaborated updated guidelines for the follow-up of abnormal cervical cytology results in Belgium, according to a review of the literature and current reimbursement of the screening tests. A proposal for the follow-up in the setting of primary HPV screening for cervical cancer is added.

(BELG J MED ONCOL 2022;16(2):60–9)

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Difficulties in diagnosis and treatment of a rare malignancy, malignant peritoneal mesothelioma

BJMO - volume 13, issue 6, october 2019

B. Dullens MD, C. Bourgain MD, PhD, W. Ceelen MD, PhD, W. Wynendaele MD, PhD


This article describes two cases of malignant peritoneal mesothelioma (MPM), which highlights the diversity of the disease and the diagnostic pitfalls. The risk factors, symptoms, molecular pathogenesis and the daily clinical relevance are discussed.

(BELG J MED ONCOL 2019;13(6): 251–254)

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The changing role of the axillary dissection in the treatment of breast cancer

BJMO - volume 6, issue 3, june 2012

A. Smeets MD, PhD, B. Carly MD, V. Cocquyt MD, PhD, M. Vanhoeij , C. Bourgain MD, PhD, E. Lifrange MD, PhD, G. Villeirs MD, PhD, M. De Ridder MD, PhD, M. Drijkoningen MD, PhD, J. Lamote , R. Van Den Broecke , M. Voordeckers , J. De Grève MD, PhD, P. Neven MD, PhD, M.R. Christiaens

The aim of this article is to highlight the recent changes in the surgical approach of the axilla in breast cancer patients. Axillary staging is dominated by the sentinel lymph node (SLN) biopsy, which is now widely practiced in clinically node negative patients. Most authors believe a SLN biopsy may even be performed in patients with a large or multifocal tumour, before neo-adjuvant systemic therapy, during pregnancy, after prior excisional biopsy and after prior mantle field radiotherapy of the breast. Intra-operative assessment of the SLN is recommended as it can identify half of all positive lymph nodes. It is generally accepted that it is safe to omit an axillary lymph node dissection (ALND) in patients with a negative SLN or with only isolated tumour cells (<0.2 mm) in the SLN. Moreover, in a subset of patients with a micro-/macrometastasis in the SLN it might not be necessary to perform a completion of ALND. We suggest to accept the option of omitting completion of ALND in frail patients with a positive sentinel lymph node on final pathology OR in these patients with, on final pathology, one or two positive SLNs AND a grade I or II tumour smaller than 4 cm AND adjuvant radiotherapy on the whole breast or chest wall. In conclusion, an increasingly tailored surgical approach is guiding the management of the axilla for women with early breast cancer. (BELG J MED ONCOL 2012;6:87–95)

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