Increasing effectiveness of cancer treatments significantly improved patient survival. More treatment options are available for frailer patients. Therefore, the importance of appropriate supportive care measures increases, particularly in high-risk patients. More data concerning potentially cardiotoxic effects of cancer therapies are available, involving multiple cardiovascular side-effects. We provide an overview of available strategies to identify the patient at increased risk for cardiotoxicity, to prevent, detect and treat cardiotoxic effects of cancer treatments and to organise follow-up in patients with documented toxicity. The main focus will be left ventricular dysfunction and heart failure, but some other frequently encountered forms of toxicity will be discussed.

(BELG J MED ONCOL 2021;15(7):367-73)