Fertility issues are a major concern for young patients diagnosed with breast cancer. This review focuses on the importance of taking treatment-related ovarian function and fertility decline into consideration by offering appropriate pre-treatment counselling. Fertility preservation options, including oocyte or embryo vitrification, cryopreservation of ovarian tissue, and administration of gonadotropin-releasing hormone analogues should be discussed before starting chemotherapy. We outline the advantages and disadvantages of each technique and review recent data on their efficacy and safety.

(BELG J MED ONCOL 2018;12(1):4–8)