This report will discuss the key lectures on head and neck cancer (HNC) presented during the 2014 annual meeting of the European Society for Medical Oncology. After addressing the novelties in immunotherapeutic therapy for HNC, the top stories on news promising drugs will be discussed. In addition some presentations discussing the set up and implementation of practice guidelines in HNC will be addressed to end of with some innovations on biomarkers.

(BELG J MED ONCOL 2014;8(4):180–3)