Quality management is a key requirement to obtain the best care for patients. In previous years, a lot of effort was made in defining quality indicators for breast cancer in Belgium. Based on EUSOMA guidelines and in collaboration with several partners, a set of quality indicators of systemic breast cancer therapy were defined. These include structure indicators (e.g. education, day clinic facilities, etc.), outcome indicators (e.g. overall survival, disease-free survival, etc.) and process indicators. The first results of some of these process indicators were presented during the 2018 annual BSMO meeting.