Articles

Oncology highlights of the EAU20 Virtual Congress and EAU20 Theme Week

BJMO - volume 14, issue 7, november 2020

H. Van Poppel MD, PhD

In light of the emergence and impact of COVID-19, the European Association of Urology (EAU) redesigned its 35th Annual EAU Congress (EAU20) into two online events, EAU20 Virtual Congress and EAU20 Theme Week, which took place from 17 to 19 July 2020 and from 20 to 26 July 2020, respectively. This article is an abridged version of the events’ oncology updates featured in the peer-reviewed conference report of the Medicom Medical Publishers.

BELG J MED ONCOL 2020;14(7):364-7)

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Early detection and diagnosis of prostate cancer in well informed men: the way forward for Europe

BJMO - volume 14, issue 7, november 2020

S. Collen , H. Van Poppel MD, PhD

SUMMARY

As 107,000 men died of prostate cancer in Europe in 2018, this is not an indolent disease. It is responsible for >10% of all male cancer deaths. Most men are not aware that it is possible to have asymptomatic prostate cancer and are uninformed about the existence and value of the PSA blood test. Early detection of prostate cancer reduces the mortality rate and can be easily cured without unbearable side effects and at a rather low price. Advanced cancer is less amenable for cure, with substantial side effects and a significant reduction in quality of life, and has a high chance of becoming metastatic and castrate-resistant. Treatment of this late stage disease is costly and prolongs life with on average only two years. Most importantly, the quality of life of these men is poor. The arguments against PSA testing are focused on issues related to over-diagnosis and overtreatment. These arguments have led in some countries to a decrease in testing, which in turn has led to an increase in too late diagnosis. In this paper, we present the results of clinical trials on early detection, the risks and benefits of early detection using PSA testing, and a way forward for the EU Cancer Plan using the current EAU scientific guidance on early detection as a basis. We conclude that PSA can now be used in a more clever fashion to ensure that men are diagnosed early enough to be able to prevent meaningful clinical disease, increase quality of life, and reduce costs for healthcare systems.

(BELG J MED ONCOL 2020;14(7):321-6)

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Update in prostate cancer 2019

BJMO - volume 14, issue 1, january 2020

S. Van Bruwaene MD, PhD, P. Dirix MD, PhD, H. Van Poppel MD, PhD

SUMMARY

The prostate cancer (PCa) landscape has changed dramatically over the past few years. New paradigm-shifting data are published nearly every month. This review aims to give a brief overview of the most important publications of 2018–2019. From the ever-lasting discussion about PSA screening, with the recent publication of the CAP trial, over diagnostics where multi-parametric MRI has caused a true revolution, to hypofractionation in radiotherapy and the dramatic treatment shifts in metastatic hormone sensitive and non-metastatic castrate resistant PCa. All exciting data that will change clinical practice.

(BELG J MED ONCOL 2020;14(1):13–21)

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EAU19: New developments in PCa imaging and trials

BJMO - volume 13, issue 7, november 2019

H. Van Poppel MD, PhD

SUMMARY

The European Association of Urology (EAU) held its 34th Annual Congress in Barcelona from the 15–19th of March, a recurring highlight for the Association and for urology in general. While the presenting of the latest EAU Guidelines, holding meetings for its Board and Sections and setting agendas for the coming year are essential to the running of the Association, it is the latest scientific developments in urology that took centre stage in Barcelona.

Scientific Congress Office Chairman Prof Arnulf Stenzl (DE) presided over the scientific programme one last time, stepping down to join the EAU Executive as Adjunct Secretary General (Science). He was congratulated on his track record and particularly the comprehensive and diverse five-day programme that greeted the nearly 12,000 participants from 127 countries in Barcelona.

This article provides some uro-oncological highlights from the 263 different scientific sessions at EAU19. For the most complete coverage, see the on-site news reports on www.eau19.org/news.

(BELG J MED ONCOL 2019;13(7):314–6)

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Case report of a patient treated locally for bone metastatic renal cell carcinoma

BJMO - volume 13, issue 7, november 2019

C. Soenens MD, G. De Meerleer MD, PhD, M. Albersen MD, PhD, H. Van Poppel MD, PhD, B. Beuselinck MD, PhD

SUMMARY

Based on a case report of a 47-year old male with primary bone metastatic renal cell carcinoma, the current treatment options are reviewed in this article.

(BELG J MED ONCOL 2019;13(7):305–8)

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EMUC18: Synergy of disciplines for optimal genitourinary cancer care

BJMO - volume 13, issue 2, march 2019

H. Van Poppel MD, PhD

SUMMARY

Marking its decade-long dedication to the goal of pursuing multidisciplinary collaboration, the 10th European Multidisciplinary Congress on Urological Cancers (EMUC18) examined the best practices, advances and future prospects in managing genitourinary malignancies. The congress also identified current dilemmas and addressed gaps in clinical practice.

(BELG J MED ONCOL 2019;13(2):63–65)

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Oncological topics presented at EAU 2018

BJMO - volume 12, issue 7, november 2018

H. Van Poppel MD, PhD

At the occasion of the Annual Congress of the European Association of Urology (EAU), a number of new trial protocols with new immuno-oncology drugs were presented for bladder and renal cancer next to the results of studies on adjuvant and neo-adjuvant chemotherapy for upper tract transitional cell carcinoma. In prostate cancer, the value of prostate-specific antigen screening and multiparametric MRI at first diagnosis was investigated, and the results of clinical trials with enzalutamide and apalutamide were reported.

(BELG J MED ONCOL 2018;12(7):339–341)

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