REIMBURSEMENT NEWS

New oncology reimbursements in Belgium

BJMO - volume 15, issue 6, october 2021

P. Specenier MD, PhD

OVERVIEW OF BELGIAN REIMBURSEMENT NEWS

 

(BELG J MED ONCOL 2021;15(6):340)

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New oncology reimbursementsin Belgium

BJMO - volume 15, issue 5, september 2021

J. Blokken PhD, PharmD, T. Feys MBA, MSc

OVERVIEW OF BELGIAN REIMBURSEMENT NEWS

(BELG J MED ONCOL 2021;15(5):264-5)

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New oncology reimbursements in Belgium

BJMO - volume 15, issue 3, may 2021

T. Feys MBA, MSc

OVERVIEW OF BELGIAN REIMBURSEMENT NEWS

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New oncology reimbursements in Belgium

BJMO - volume 15, issue 2, march 2021

P. Specenier MD, PhD

OVERVIEW OF BELGIAN REIMBURSEMENT NEWS

(BELG J MED ONCOL 2021;15(2):87-91)

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New oncology reimbursements in Belgium

BJMO - volume 15, issue 1, january 2021

P. Specenier MD, PhD

LORVIQUA® (LORLATINIB)

Lorviqua® (lorlatinib) is reimbursed for the treatment of patients with ALK-positive advanced non-small cell carcinoma who progressed during or after prior therapy with a second-generation ALK tyrosine kinase inhibitor (TKI). The use of lorlatinib in the treatment of ALK-positive advanced NSCLC after treatment with at least one second-generation ALK TKI was investigated in a single-arm, multicentre phase I/II study enrolling 139 patients. Patients received lorlatinib orally at the recommended dose of 100 mg once daily, continuously. The primary efficacy endpoint in the phase II portion of the study was objective response rate (ORR), including intracranial (IC)-ORR, as per Independent Central Review (ICR) according to modified response evaluation criteria in solid tumours (modified RECIST version 1.1). In the overall efficacy population of 139 patients, 56 patients (40.3%) had a confirmed objective response by ICR. The ORR was 42.9% (95% confidence interval [CI] 24.5-62.8) in the 28 patients who received one prior ALK TKI and 39.6% (95% CI 30.5- 49.4) in the 111 patients who received ≥2 prior ALK TKI. Median progression-free survival (PFS) was 5.5 months (95% CI 2.9-8.2) and 6.9 months (95% CI 5.4-9.5), respectively. The IC-ORR was 66.7% (95% CI 29.9-92.5) in patients who received one prior ALK TKI and 52.1% (95% CI 37.2-66.7) in patients who received ≥2 prior ALK TKI.

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New oncology reimbursements in Belgium

BJMO - volume 13, issue 7, november 2019

Tom Feys MBA, MSc

Overview of Belgian reimbursement news

(BELG J MED ONCOL 2019;13(7):317)

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New oncology reimbursements in Belgium

BJMO - volume 13, issue 6, october 2019

P. Specenier MD, PhD

Overview of Belgian reimbursement news

(BELG J MED ONCOL 2019;13(6):266–267)

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