Relevent literature for your daily practice selected by: Didier Verhoeven

May 2021 Editor's pick Tom Feys

THE GLOBAL BREAST CANCER INITIATIVE: A STRATEGIC COLLABORATION TO STRENGTHEN HEALTHCARE FOR NON-COMMUNICABLE DISEASES

As breast cancer deaths disproportionately affect women in low- and middle-income countries, the time is now to engage global partners to coordinate sustainable efforts and achieve favourable outcomes for these patients. Therefore, the WHO launched the Global Breast Cancer Initiative that focuses on three main aspects of breast cancer care; health promotion, timely diagnosis and comprehensive treatment… Read more

EVALUATING ELIGIBILITY CRITERIA OF ONCOLOGY TRIALS USING REAL-WORLD DATA AND ARTIFICIAL INTELLIGENCE

To date, overly restrictive eligibility criteria for clinical trials often limit the access of cancer patients to potentially beneficial treatments. Interestingly, however, recent real-world data within the computational framework of Trial Pathfinder revealed that many common criteria only had minimal effect on the trial hazard ratios while the pool of eligible patients on average more than doubled upon these less restrictive criteria… Read more

TARGETING PAN-ESSENTIAL GENES IN CANCER: CHALLENGES AND OPPORTUNITIES

Despite remarkable successes in the clinic, the development of targeted anticancer therapies remains to be challenging with disappointingly high failure rates. This can, at least in part, be attributed to the misapplication of targeted therapy directed against pan-essential genes, whereby efficacy is attenuated by dose-limiting toxicity. Recognising the challenges and opportunities associated with these drugs is of utmost importance for the next generation of cancer therapeutics… Read more

DISCREPANCIES IN ACCESS TO ANTICANCER MEDICATIONS FOR CHILDREN AND ADOLESCENTS ACROSS EUROPE

Accessibility to anticancer medications reportedly vary between European nations. Investigating this in a paediatric setting, the Joint Action on Rare Cancers (JARC) health programme distributed surveys to health professionals and parents. Variation in paediatric regulatory approval, financial burden and child-friendly formulations were reported. Crucially, only 44% of medicines included in the survey were reported as being always available… Read more

EVALUATION OF TELEMEDICINE PRACTICES DURING THE COVID-19 PANDEMIC FOR ONCOLOGY PATIENTS

The interest in the use of telemedicine had a boost during the COVID-19 pandemic. Assessing this consultation modality in an oncological setting, the Tel Aviv Medical Center found that out of the 172 patients who received a telemedicine consultation, 93% reported that their concerns were adequately addressed. In fact, more than four out of five patients indicated that they would consider a telemedicine consultation again in the future… Read more

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